View source for 8hdj


==Periplasmic domain of RsgI2 of Clostridium thermocellum==
<StructureSection load='8hdj' size='340' side='right'caption='[[8hdj]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8hdj]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus_DSM_1313 Acetivibrio thermocellus DSM 1313]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HDJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HDJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hdj OCA], [https://pdbe.org/8hdj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hdj RCSB], [https://www.ebi.ac.uk/pdbsum/8hdj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hdj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RSGI2_ACET2 RSGI2_ACET2] Anti-sigma factor for SigI2. Negatively regulates SigI2 activity through direct interaction. Binding of the polysaccharide substrate to the extracellular C-terminal sensing domain of RsgI2 may induce a conformational change in its N-terminal cytoplasmic region, leading to the release and activation of SigI2.[UniProtKB:A3DBH1]
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</StructureSection>
[[Category: Acetivibrio thermocellus DSM 1313]]
[[Category: Large Structures]]
[[Category: Chen C]]
[[Category: Dong S]]
[[Category: Feng YG]]