View source for 8hei


==Crystal structure of CTSB in complex with E64d==
<StructureSection load='8hei' size='340' side='right'caption='[[8hei]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8hei]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HEI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HEI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E6D:ETHYL+(3S)-3-HYDROXY-4-({(2S)-4-METHYL-1-[(3-METHYLBUTYL)AMINO]-1-OXOPENTAN-2-YL}AMINO)-4-OXOBUTANOATE'>E6D</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hei FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hei OCA], [https://pdbe.org/8hei PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hei RCSB], [https://www.ebi.ac.uk/pdbsum/8hei PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hei ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Li D]]
[[Category: Sun L]]
[[Category: Wang H]]
[[Category: Yang H]]