View source for 8hfp


==Crystal structure of the methyl-CpG-binding domain of SETDB2 in complex with the cysteine-rich domain of C11orf46 protein==
<StructureSection load='8hfp' size='340' side='right'caption='[[8hfp]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8hfp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HFP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hfp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hfp OCA], [https://pdbe.org/8hfp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hfp RCSB], [https://www.ebi.ac.uk/pdbsum/8hfp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hfp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AL14E_HUMAN AL14E_HUMAN] Through its interaction with ARL14 and MYO1E, may connect MHC class II-containing cytoplasmic vesicles to the actin network and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.<ref>PMID:21458045</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Ariyoshi M]]
[[Category: Mahana Y]]
[[Category: Shirakawa M]]