View source for 8hpz


==Crystal structure of the MlaD domain of the MlaD protein from Escherichia coli (Form I)==
<StructureSection load='8hpz' size='340' side='right'caption='[[8hpz]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8hpz]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HPZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO2:CARBON+DIOXIDE'>CO2</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hpz OCA], [https://pdbe.org/8hpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hpz RCSB], [https://www.ebi.ac.uk/pdbsum/8hpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hpz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MLAD_ECOLI MLAD_ECOLI] Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane (PubMed:19383799, PubMed:27529189). MlaD functions in substrate binding with strong affinity for phospholipids and modulates ATP hydrolytic activity of the complex (PubMed:27529189).<ref>PMID:19383799</ref> <ref>PMID:27529189</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Dutta A]]
[[Category: Kanaujia SP]]