View source for 8idx


==Structure of p205 HIN==
<StructureSection load='8idx' size='340' side='right'caption='[[8idx]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8idx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IDX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IDX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8idx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8idx OCA], [https://pdbe.org/8idx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8idx RCSB], [https://www.ebi.ac.uk/pdbsum/8idx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8idx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IFI5B_MOUSE IFI5B_MOUSE] May act as a transcriptional regulator in the myeloid lineage. Inhibits cell growth via p53/TP53 and RB1-dependent and independent pathways.<ref>PMID:15342947</ref> <ref>PMID:16458891</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Jin TC]]
[[Category: Li YL]]