View source for 8is0


==Carbon Sulfoxide lyase - Y106F==
<StructureSection load='8is0' size='340' side='right'caption='[[8is0]], [[Resolution|resolution]] 3.02&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8is0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8IS0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8IS0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.02&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DHA:2-AMINO-ACRYLIC+ACID'>DHA</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8is0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8is0 OCA], [https://pdbe.org/8is0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8is0 RCSB], [https://www.ebi.ac.uk/pdbsum/8is0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8is0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EGTE_MYCS2 EGTE_MYCS2] Probably catalyzes the conversion of hercynylcysteine sulfoxide to ergothioneine. Ergothioneine is a secreted antioxidant that protects mycobacterium from oxidative stress.<ref>PMID:20420449</ref> <ref>PMID:23629716</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycolicibacterium smegmatis MC2 155]]
[[Category: Gong WM]]
[[Category: Liu L]]
[[Category: Wei LL]]