View source for 8j71


==Selenomethionine mutant (L601Sem/L654Sem) of SAND domain of protein SP140 with DNA==
<StructureSection load='8j71' size='340' side='right'caption='[[8j71]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8j71]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8J71 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8J71 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8j71 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8j71 OCA], [https://pdbe.org/8j71 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8j71 RCSB], [https://www.ebi.ac.uk/pdbsum/8j71 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8j71 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SP140_HUMAN SP140_HUMAN] Component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Li HT]]
[[Category: Liu WQ]]