View source for 8jpf


==Focused refiment structure of NTSR1 in NTSR1-GRK2-Galpha(q) complexes==
<StructureSection load='8jpf' size='340' side='right'caption='[[8jpf]], [[Resolution|resolution]] 3.02&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8jpf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JPF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JPF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.02&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SRW:2-[{2-(1-fluorocyclopropyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]quinazolin-6-yl}(methyl)amino]ethan-1-ol'>SRW</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jpf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jpf OCA], [https://pdbe.org/8jpf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jpf RCSB], [https://www.ebi.ac.uk/pdbsum/8jpf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jpf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NTR1_HUMAN NTR1_HUMAN] Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Duan J]]
[[Category: Ji Y]]
[[Category: Liu H]]
[[Category: Xu HE]]
[[Category: Yuan Q]]
[[Category: Zhao F]]