View source for 8jr5


==Crystal structure of Hendra Virus attachment(G) glycoprotein mutant S586N==
<StructureSection load='8jr5' size='340' side='right'caption='[[8jr5]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8jr5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hendra_virus_horse/Australia/Hendra/1994 Hendra virus horse/Australia/Hendra/1994]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JR5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jr5 OCA], [https://pdbe.org/8jr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jr5 RCSB], [https://www.ebi.ac.uk/pdbsum/8jr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jr5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLYCP_HENDH GLYCP_HENDH] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of glycoprotein G to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity).
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</StructureSection>
[[Category: Hendra virus horse/Australia/Hendra/1994]]
[[Category: Large Structures]]
[[Category: Chen W]]
[[Category: Huang XY]]
[[Category: Li YH]]
[[Category: Xu JJ]]