View source for 8jtp


==Crystal structure of apo Enoyl-Acyl Carrier Protein Reductase (FabI) from Klebsiella pneumoniae==
<StructureSection load='8jtp' size='340' side='right'caption='[[8jtp]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8jtp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_subsp._pneumoniae Klebsiella pneumoniae subsp. pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8JTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8JTP FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8jtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8jtp OCA], [https://pdbe.org/8jtp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8jtp RCSB], [https://www.ebi.ac.uk/pdbsum/8jtp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8jtp ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A1Y0Q1M7_KLEPN A0A1Y0Q1M7_KLEPN] Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism and in the biotin biosynthesis.[ARBA:ARBA00025542]
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</StructureSection>
[[Category: Klebsiella pneumoniae subsp. pneumoniae]]
[[Category: Large Structures]]
[[Category: Biswas S]]
[[Category: Kushwaha GS]]
[[Category: Suar M]]