View source for 8ofz


==Molecular Mechanism of trypanosomal AQP2==
<StructureSection load='8ofz' size='340' side='right'caption='[[8ofz]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ofz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OFZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OFZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ofz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ofz OCA], [https://pdbe.org/8ofz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ofz RCSB], [https://www.ebi.ac.uk/pdbsum/8ofz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ofz ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AQP2_TRYBB AQP2_TRYBB] Mediates water and glycerol transport across cell membranes (PubMed:15294911, PubMed:21471730). Permeable to urea (PubMed:15294911). Permeable to methylamine/methylammonium (PubMed:16889642). Permeable to dihydroxyacetone (PubMed:15294911).<ref>PMID:15294911</ref> <ref>PMID:16889642</ref> <ref>PMID:21471730</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Matusevicius M]]
[[Category: Weyand SN]]
[[Category: Yamashita K]]