View source for 8onh


==Variant Surface Glycoprotein VSG11wt-Oil==
<StructureSection load='8onh' size='340' side='right'caption='[[8onh]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8onh]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ONH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ONH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8onh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8onh OCA], [https://pdbe.org/8onh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8onh RCSB], [https://www.ebi.ac.uk/pdbsum/8onh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8onh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B3GVS7_TRYBB B3GVS7_TRYBB] VSG forms a coat on the surface of the parasite. The trypanosome evades the immune response of the host by expressing a series of antigenically distinct VSGs from an estimated 1000 VSG genes.[ARBA:ARBA00002523]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trypanosoma brucei brucei]]
[[Category: Foti K]]
[[Category: Gkeka A]]
[[Category: Stebbins CE]]
[[Category: Vlachou EP]]
[[Category: Zeelen JP]]