View source for 8pmm


==Structure of Nal1 protein, allele SPIKE from japonica rice, construct 31-458==
<StructureSection load='8pmm' size='340' side='right'caption='[[8pmm]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8pmm]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryza_sativa_Japonica_Group Oryza sativa Japonica Group]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PMM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PMM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pmm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pmm OCA], [https://pdbe.org/8pmm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pmm RCSB], [https://www.ebi.ac.uk/pdbsum/8pmm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pmm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NAL1_ORYSJ NAL1_ORYSJ] Involved in the regulation of lateral leaf growth (PubMed:18562767, PubMed:22179305, PubMed:23985993). May be involved in the regulation of basipetal polar auxin transport (PAT) and vascular patterning in leaves (PubMed:18562767). Controls photosynthesis rate by regulating carboxylation efficiency and consequently photosynthesis rate (PubMed:23985993). Controls panicle and spikelet numbers, and grain yield (PubMed:23985993, PubMed:24297875, PubMed:24795339).<ref>PMID:18562767</ref> <ref>PMID:22179305</ref> <ref>PMID:23985993</ref> <ref>PMID:24297875</ref> <ref>PMID:24795339</ref> 
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== Publication Abstract from PubMed ==
NARROW LEAF1 (NAL1) exerts a multifaceted influence on leaf morphology and crop yield. Recent crystal study proposed that histidine 233 (H233) is part of the catalytic triad. Here we report that unlike suggested previously, H234 instead of H233 is a component of the catalytic triad alongside residues D291 and S385 in NAL1. Remarkably, residue 233 unexpectedly plays a pivotal role in regulating NAL1's proteolytic activity. These findings establish a strong foundation for utilizing NAL1 in breeding programs aimed at improving crop yield.

The catalytic triad of rice NARROW LEAF1 involves H234.,Huang LY, Liu NN, Chen WF, Ai X, Li HH, Zhang ZL, Hou XM, Fosse P, Mauffret O, Lei DS, Rety S, Xi XG Nat Plants. 2024 May;10(5):743-748. doi: 10.1038/s41477-024-01668-1. Epub 2024 , Apr 10. PMID:38600265<ref>PMID:38600265</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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<div class="pdbe-citations 8pmm" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oryza sativa Japonica Group]]
[[Category: Huang LY]]
[[Category: Rety S]]
[[Category: Xi XG]]