View source for 8pni


==Chorismate mutase==
<StructureSection load='8pni' size='340' side='right'caption='[[8pni]], [[Resolution|resolution]] 1.21&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8pni]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PNI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PNI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.21&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pni FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pni OCA], [https://pdbe.org/8pni PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pni RCSB], [https://www.ebi.ac.uk/pdbsum/8pni PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pni ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CHMU_PSEAE CHMU_PSEAE] Catalyzes the Claisen rearrangement of chorismate to prephenate. The joint presence of this enzyme together with cyclohexadienyl dehydratase and aromatic aminotransferase in the periplasmic compartment comprises a complete three-step chorismate to phenylalanine pathway and accounts for the so called hidden overflow pathway to phenylalanine in P.aeruginosa, in which two possible routes for it exists, namely either via phenylpyruvate or L-arogenate.[UniProtKB:P0A9J8]<ref>PMID:11532214</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Cordara G]]
[[Category: Khatanbaatar T]]
[[Category: Krengel U]]