View source for 8pnm


==Structure of human KCTD15 BTB domain mutant G88D crystal form 2==
<StructureSection load='8pnm' size='340' side='right'caption='[[8pnm]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8pnm]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PNM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pnm OCA], [https://pdbe.org/8pnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pnm RCSB], [https://www.ebi.ac.uk/pdbsum/8pnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pnm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KCD15_HUMAN KCD15_HUMAN] During embryonic development, interferes with neural crest formation (By similarity). Inhibits AP2 transcriptional activity by interaction with its activation domain.<ref>PMID:23382213</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bradshaw W]]
[[Category: Bullock AN]]
[[Category: Chalk R]]
[[Category: Chen Z]]
[[Category: Cros J]]
[[Category: Cruz Walma DA]]
[[Category: Richardson W]]
[[Category: Wilkie A]]