View source for 8ppa


==Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with D-myo-inositol 1,4,6-trisphosphate/AMP-PNP/Mn==
<StructureSection load='8ppa' size='340' side='right'caption='[[8ppa]], [[Resolution|resolution]] 1.73&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ppa]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PPA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PPA FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.73&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=06G:D-myo-inositol+1,4,6-trisphosphate'>06G</scene>, <scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ppa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ppa OCA], [https://pdbe.org/8ppa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ppa RCSB], [https://www.ebi.ac.uk/pdbsum/8ppa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ppa ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IP3KA_HUMAN IP3KA_HUMAN] 
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Gonzalez B]]
[[Category: Marquez-Monino MA]]