View source for 8ppd


==Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with DL-6-deoxy-6-hydroxy-methyl-scyllo-inositol 1,2,4-trisphosphate/ATP/Mn==
<StructureSection load='8ppd' size='340' side='right'caption='[[8ppd]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ppd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PPD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.77&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=75I:DL-6-deoxy-6-hydroxy-methyl-scyllo-inositol+1,2,4-trisphosphate'>75I</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ppd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ppd OCA], [https://pdbe.org/8ppd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ppd RCSB], [https://www.ebi.ac.uk/pdbsum/8ppd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ppd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IP3KA_HUMAN IP3KA_HUMAN] 
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Gonzalez B]]
[[Category: Marquez-Monino MA]]