View source for 8ppi


==Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with beta-D-glucopyranosylmethanol 3,4,1'-trisphosphate/ATP/Mn==
<StructureSection load='8ppi' size='340' side='right'caption='[[8ppi]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8ppi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PPI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PPI FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=69I:beta-D-glucopyranosylmethanol+3,4,1-trisphosphate'>69I</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ppi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ppi OCA], [https://pdbe.org/8ppi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ppi RCSB], [https://www.ebi.ac.uk/pdbsum/8ppi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ppi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/IP3KA_HUMAN IP3KA_HUMAN] 
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Gonzalez B]]
[[Category: Marquez-Monino MA]]