View source for 8pts


==human GUK1 in complex with compound AT8001==
<StructureSection load='8pts' size='340' side='right'caption='[[8pts]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8pts]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PTS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PTS FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EIF:[(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-1~{H}-purin-9-yl)-4-fluoranyl-4-methyl-3-oxidanyl-oxolan-2-yl]methyl+dihydrogen+phosphate'>EIF</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pts FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pts OCA], [https://pdbe.org/8pts PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pts RCSB], [https://www.ebi.ac.uk/pdbsum/8pts PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pts ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/KGUA_HUMAN KGUA_HUMAN] Essential for recycling GMP and indirectly, cGMP.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Canard B]]
[[Category: Ferron F]]
[[Category: Zimberger C]]