View source for 8pvj


==Structure of lumazine synthase determined by cryoEM at 100 keV==
<StructureSection load='8pvj' size='340' side='right'caption='[[8pvj]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8pvj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PVJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PVJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pvj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pvj OCA], [https://pdbe.org/8pvj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pvj RCSB], [https://www.ebi.ac.uk/pdbsum/8pvj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pvj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RISB_AQUAE RISB_AQUAE] Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.<ref>PMID:12603336</ref> <ref>PMID:11237620</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Aquifex aeolicus]]
[[Category: Large Structures]]
[[Category: Cannone G]]
[[Category: Chen S]]
[[Category: Dalby J]]
[[Category: Dickerson JL]]
[[Category: El-Gomati MM]]
[[Category: Gittins O]]
[[Category: Henderson R]]
[[Category: Hutchings KA]]
[[Category: Lee Y]]
[[Category: McMullan G]]
[[Category: Meffert M]]
[[Category: Mihaylov D]]
[[Category: Naydenova K]]
[[Category: Peet MJ]]
[[Category: Russo CJ]]
[[Category: Schulze-Briese C]]
[[Category: Sobhy M]]
[[Category: Wells T]]
[[Category: Wilson H]]
[[Category: Yamashita K]]