View source for 8pw3


==Mycobacterium smegmatis inosine monophosphate dehydrogenase (IMPDH) apo form==
<StructureSection load='8pw3' size='340' side='right'caption='[[8pw3]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8pw3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PW3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PW3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.507&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pw3 OCA], [https://pdbe.org/8pw3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pw3 RCSB], [https://www.ebi.ac.uk/pdbsum/8pw3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pw3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0QSU3_MYCS2 A0QSU3_MYCS2] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Mycolicibacterium smegmatis MC2 155]]
[[Category: Bulvas O]]
[[Category: Kouba T]]
[[Category: Pichova I]]