View source for 8q9w


==Crystal structure of HsRNMT complexed with sinefungin and GMP-PnP==
<StructureSection load='8q9w' size='340' side='right'caption='[[8q9w]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8q9w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q9W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q9W FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q9w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q9w OCA], [https://pdbe.org/8q9w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q9w RCSB], [https://www.ebi.ac.uk/pdbsum/8q9w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q9w ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MCES_HUMAN MCES_HUMAN] mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC.<ref>PMID:9790902</ref> <ref>PMID:9705270</ref> <ref>PMID:10347220</ref> <ref>PMID:22099306</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Fyfe PK]]
[[Category: Petit AP]]