View source for 8qau


==Outer kinetochore Ndc80-Dam1 alpha/beta-tubulin complex==
<StructureSection load='8qau' size='340' side='right'caption='[[8qau]], [[Resolution|resolution]] 3.54&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qau]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QAU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QAU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.54&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TA1:TAXOL'>TA1</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qau FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qau OCA], [https://pdbe.org/8qau PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qau RCSB], [https://www.ebi.ac.uk/pdbsum/8qau PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qau ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NDC80_YEAST NDC80_YEAST] Acts as a component of the essential kinetochore-associated NDC80 complex, which is involved in chromosome segregation and spindle checkpoint activity.<ref>PMID:10409732</ref> <ref>PMID:11266451</ref> <ref>PMID:12514103</ref> <ref>PMID:9585415</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Sus scrofa]]
[[Category: Barford D]]
[[Category: Muir KW]]