View source for 8qc1


==Respiratory complex I from Paracoccus denitrificans in MSP2N2 nanodiscs (ND4 & ND5 focus refinement)==
<StructureSection load='8qc1' size='340' side='right'caption='[[8qc1]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qc1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Paracoccus_denitrificans_PD1222 Paracoccus denitrificans PD1222]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QC1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QC1 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qc1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qc1 OCA], [https://pdbe.org/8qc1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qc1 RCSB], [https://www.ebi.ac.uk/pdbsum/8qc1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qc1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A1B480_PARDP A1B480_PARDP] NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.[ARBA:ARBA00002378]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Paracoccus denitrificans PD1222]]
[[Category: Bridges HR]]
[[Category: Hirst J]]
[[Category: Ivanov BS]]