View source for 8qeb


==S. cerevisia Niemann-Pick type C protein NCR1 in GDN at pH 7.5==
<StructureSection load='8qeb' size='340' side='right'caption='[[8qeb]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qeb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QEB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QEB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ERG:ERGOSTEROL'>ERG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qeb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qeb OCA], [https://pdbe.org/8qeb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qeb RCSB], [https://www.ebi.ac.uk/pdbsum/8qeb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qeb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NPC1_YEAST NPC1_YEAST] Involved in sphingolipid trafficking. May recycle sphingolipids between cellular membranous compartments.<ref>PMID:14970192</ref> <ref>PMID:16138904</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Dedic E]]
[[Category: Frain KM]]
[[Category: Nel L]]
[[Category: Olesen E]]
[[Category: Panyella Pedersen B]]
[[Category: Stokes D]]