View source for 8qhc


==Cryo-EM structure of SidH from Legionella pneumophila in complex with LubX==
<StructureSection load='8qhc' size='340' side='right'caption='[[8qhc]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qhc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_'BL21-Gold(DE3)pLysS_AG' Escherichia coli 'BL21-Gold(DE3)pLysS AG'] and [https://en.wikipedia.org/wiki/Legionella_pneumophila Legionella pneumophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QHC FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3AU:3-[(3S)-3-AMINO-3-CARBOXYPROPYL]URIDINE+5-(DIHYDROGEN+PHOSPHATE)'>3AU</scene>, <scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MU:5-METHYLURIDINE+5-MONOPHOSPHATE'>5MU</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qhc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qhc OCA], [https://pdbe.org/8qhc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qhc RCSB], [https://www.ebi.ac.uk/pdbsum/8qhc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qhc ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/E2QJ06_ECOLX E2QJ06_ECOLX] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118]
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</StructureSection>
[[Category: Large Structures]]
[[Category: Legionella pneumophila]]
[[Category: Adams M]]
[[Category: Bhogaraju S]]
[[Category: Sharma R]]