View source for 8qjh


==Connexin-32 gap junction channel in complex with mefloquine==
<StructureSection load='8qjh' size='340' side='right'caption='[[8qjh]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qjh]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QJH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QJH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.91&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qjh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qjh OCA], [https://pdbe.org/8qjh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qjh RCSB], [https://www.ebi.ac.uk/pdbsum/8qjh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qjh ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/CXB1_HUMAN CXB1_HUMAN] X-linked Charcot-Marie-Tooth disease type 1;X-linked progressive cerebellar ataxia. The disease is caused by mutations affecting the gene represented in this entry.  The gene represented in this entry may act as a disease modifier.
== Function ==
[https://www.uniprot.org/uniprot/CXB1_HUMAN CXB1_HUMAN] One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Han Y]]
[[Category: Korkhov VM]]
[[Category: Lavriha P]]