View source for 8qqg


==Structure of BRAF in Complex With Exarafenib (KIN-2787).==
<StructureSection load='8qqg' size='340' side='right'caption='[[8qqg]], [[Resolution|resolution]] 2.98&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qqg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QQG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.979&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=WJ9:(3~{S})-~{N}-[4-methyl-3-[2-morpholin-4-yl-6-[[(2~{R})-1-oxidanylpropan-2-yl]amino]pyridin-4-yl]phenyl]-3-[2,2,2-tris(fluoranyl)ethyl]pyrrolidine-1-carboxamide'>WJ9</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qqg OCA], [https://pdbe.org/8qqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qqg RCSB], [https://www.ebi.ac.uk/pdbsum/8qqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qqg ProSAT]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chen YK]]
[[Category: Costanzi E]]
[[Category: Kania R]]
[[Category: Schmitt A]]