View source for 8qvx


==Structure of the PBD of human SRP68/72 (cryoSPARC 3DFlex)==
<StructureSection load='8qvx' size='340' side='right'caption='[[8qvx]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qvx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QVX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QVX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qvx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qvx OCA], [https://pdbe.org/8qvx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qvx RCSB], [https://www.ebi.ac.uk/pdbsum/8qvx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qvx ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SRP68_HUMAN SRP68_HUMAN] Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function.
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Ataide SF]]
[[Category: Feng J]]
[[Category: Greber BJ]]
[[Category: Koh AF]]
[[Category: Kotecha A]]
[[Category: Zhong Y]]