View source for 8qyu


==Beta-cardiac myosin S1 fragment in the pre-powerstroke state complexed to Omecamtiv mecarbil==
<StructureSection load='8qyu' size='340' side='right'caption='[[8qyu]], [[Resolution|resolution]] 1.96&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qyu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QYU FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.96&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2OW:METHYL+4-(2-FLUORO-3-{[(6-METHYLPYRIDIN-3-YL)CARBAMOYL]AMINO}BENZYL)PIPERAZINE-1-CARBOXYLATE'>2OW</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene>, <scene name='pdbligand=VO4:VANADATE+ION'>VO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qyu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qyu OCA], [https://pdbe.org/8qyu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qyu RCSB], [https://www.ebi.ac.uk/pdbsum/8qyu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qyu ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYH7_BOVIN MYH7_BOVIN] Muscle contraction.
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</StructureSection>
[[Category: Bos taurus]]
[[Category: Large Structures]]
[[Category: Auguin D]]
[[Category: David A]]
[[Category: Houdusse A]]
[[Category: Kikuti C]]
[[Category: Rety S]]
[[Category: Robert-Paganin J]]