View source for 8qzv


==Crystal structure of translation factor eIF5A from Trichomonas vaginalis==
<StructureSection load='8qzv' size='340' side='right'caption='[[8qzv]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8qzv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichomonas_vaginalis Trichomonas vaginalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QZV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QZV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qzv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qzv OCA], [https://pdbe.org/8qzv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qzv RCSB], [https://www.ebi.ac.uk/pdbsum/8qzv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qzv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D5MC19_TRIVA D5MC19_TRIVA] Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.[RuleBase:RU362005]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Trichomonas vaginalis]]
[[Category: Grudnik P]]
[[Category: Wator E]]
[[Category: Wilk P]]