View source for 8rbf


==CryoEM structure of the post-powerstroke actomyosin-5a complex==
<StructureSection load='8rbf' size='340' side='right'caption='[[8rbf]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8rbf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RBF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RBF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rbf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rbf OCA], [https://pdbe.org/8rbf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rbf RCSB], [https://www.ebi.ac.uk/pdbsum/8rbf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rbf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYO5A_MOUSE MYO5A_MOUSE] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation.<ref>PMID:22908308</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Atherton JL]]
[[Category: Forgacs E]]
[[Category: Galkin VE]]
[[Category: Klebl DP]]
[[Category: Knight PJ]]
[[Category: McMillan SN]]
[[Category: Muench SP]]
[[Category: Risi C]]
[[Category: Scarff CA]]
[[Category: Sobott F]]
[[Category: Stofella M]]
[[Category: Virok B]]
[[Category: White HD]]
[[Category: Winkelmann DA]]