View source for 8red


==Cryo-EM structure of bacterial RNA polymerase-sigma54 initial transcribing complex - 8nt complex==
<StructureSection load='8red' size='340' side='right'caption='[[8red]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8red]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Klebsiella_oxytoca Klebsiella oxytoca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RED FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8red FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8red OCA], [https://pdbe.org/8red PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8red RCSB], [https://www.ebi.ac.uk/pdbsum/8red PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8red ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/RPOA_ECOLI RPOA_ECOLI] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.[HAMAP-Rule:MF_00059]
__TOC__
</StructureSection>
[[Category: Escherichia coli K-12]]
[[Category: Klebsiella oxytoca]]
[[Category: Large Structures]]
[[Category: Gao F]]
[[Category: Zhang X]]