View source for 8rtk


==X-ray structure of lysozyme obtained upon reaction with [VIVO(8-HQ)2] in sodium formate==
<StructureSection load='8rtk' size='340' side='right'caption='[[8rtk]], [[Resolution|resolution]] 1.21&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8rtk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RTK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RTK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.21&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1H23:2,2-spirobi[3-oxa-1$l^{5}-aza-2$l^{10}-vanadatricyclo[6.3.1.0^{4,12}]dodeca-1,1(12),4,6,8,10-hexaene]+2,2-dioxide'>A1H23</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=VVB:bis(oxidanyl)vanadium'>VVB</scene>, <scene name='pdbligand=VVO:oxovanadium(2+)'>VVO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rtk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rtk OCA], [https://pdbe.org/8rtk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rtk RCSB], [https://www.ebi.ac.uk/pdbsum/8rtk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rtk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Ferraro G]]
[[Category: Merlino A]]
[[Category: Paolillo M]]