View source for 8rwb


==Crystal structure of ULBP6 in complex with a blocking antibody==
<StructureSection load='8rwb' size='340' side='right'caption='[[8rwb]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8rwb]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RWB FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.307&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rwb OCA], [https://pdbe.org/8rwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rwb RCSB], [https://www.ebi.ac.uk/pdbsum/8rwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rwb ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ULBP6_HUMAN ULBP6_HUMAN] Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity.<ref>PMID:19658097</ref> <ref>PMID:28559451</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Bahrami Dizicheh Z]]
[[Category: Bharill S]]
[[Category: Chen I]]
[[Category: Doamekpor S]]
[[Category: Fuh G]]
[[Category: Ivic N]]
[[Category: Koenig P]]
[[Category: Wu Y]]