View source for 8szl


==Human liver-type glutaminase (Apo form)==
<StructureSection load='8szl' size='340' side='right'caption='[[8szl]], [[Resolution|resolution]] 3.12&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8szl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8SZL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8SZL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.12&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8szl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8szl OCA], [https://pdbe.org/8szl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8szl RCSB], [https://www.ebi.ac.uk/pdbsum/8szl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8szl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GLSL_HUMAN GLSL_HUMAN] Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation.<ref>PMID:20378837</ref> 
== References ==
<references/>
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Aplin C]]
[[Category: Cerione RA]]
[[Category: Feng S]]
[[Category: Milano SK]]
[[Category: Nguyen T-TT]]