View source for 8t60


==CryoEM structure of an inward-facing MelBSt at a Na(+)-bound and sugar low-affinity conformation==
<StructureSection load='8t60' size='340' side='right'caption='[[8t60]], [[Resolution|resolution]] 3.29&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8t60]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8T60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8T60 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.29&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8t60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8t60 OCA], [https://pdbe.org/8t60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8t60 RCSB], [https://www.ebi.ac.uk/pdbsum/8t60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8t60 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MELB_SALTY MELB_SALTY] Responsible for melibiose transport. It is capable of using hydrogen, sodium, and lithium cations as coupling cations for cotransport, depending on the particular sugar transported (symport system).
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</StructureSection>
[[Category: Large Structures]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Synthetic construct]]
[[Category: Guan L]]