View source for 8tlj


==CDCA7 (Mouse) Binds Non-B-form 32-mer DNA oligo Containing a 5mC==
<StructureSection load='8tlj' size='340' side='right'caption='[[8tlj]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8tlj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TLJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TLJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tlj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tlj OCA], [https://pdbe.org/8tlj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tlj RCSB], [https://www.ebi.ac.uk/pdbsum/8tlj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tlj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CDCA7_MOUSE CDCA7_MOUSE] Participates in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Insufficient to induce tumorigenicity when overexpressed but contributes to MYC-mediated tumorigenesis. May play a role as transcriptional regulator (By similarity).<ref>PMID:16580749</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Cheng X]]
[[Category: Horton JR]]
[[Category: Ren R]]