View source for 8tsm


==Crystal structure of chicken Netrin-1 LN LE1-2==
<StructureSection load='8tsm' size='340' side='right'caption='[[8tsm]], [[Resolution|resolution]] 3.90&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8tsm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TSM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TSM FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.9&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tsm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tsm OCA], [https://pdbe.org/8tsm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tsm RCSB], [https://www.ebi.ac.uk/pdbsum/8tsm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tsm ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NET1_CHICK NET1_CHICK] Netrins control guidance of CNS commissural axons and peripheral motor axons. Promotes neurite outgrowth from commissural axons but acts as a chemorepellent for trochlear motor axons. These effects are mediated by distinct receptors.
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</StructureSection>
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Heide F]]
[[Category: Rafiei F]]
[[Category: Stetefeld J]]