View source for 8tul


==Cryo-EM structure of the human MRS2 magnesium channel under Mg2+ condition==
<StructureSection load='8tul' size='340' side='right'caption='[[8tul]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8tul]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8TUL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8TUL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8tul FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8tul OCA], [https://pdbe.org/8tul PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8tul RCSB], [https://www.ebi.ac.uk/pdbsum/8tul PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8tul ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MRS2_HUMAN MRS2_HUMAN] Magnesium transporter that mediates the influx of magnesium into the mitochondrial matrix (PubMed:11401429, PubMed:18384665). Required for normal expression of the mitochondrial respiratory complex I subunits (PubMed:18384665).<ref>PMID:11401429</ref> <ref>PMID:18384665</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Balaraman J]]
[[Category: Lai LTF]]
[[Category: Matthies D]]
[[Category: Zhou F]]