View source for 8uhe


==Structure of the far-red light-absorbing allophycocyanin core expressed during FaRLiP==
<StructureSection load='8uhe' size='340' side='right'caption='[[8uhe]], [[Resolution|resolution]] 2.78&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8uhe]] is a 19 chain structure with sequence from [https://en.wikipedia.org/wiki/Synechococcus_sp._PCC_7335 Synechococcus sp. PCC 7335]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UHE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UHE FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.78&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CYC:PHYCOCYANOBILIN'>CYC</scene>, <scene name='pdbligand=M1V:MESOBILIVERDIN+IX(ALPHA)'>M1V</scene>, <scene name='pdbligand=MEN:N-METHYL+ASPARAGINE'>MEN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uhe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uhe OCA], [https://pdbe.org/8uhe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uhe RCSB], [https://www.ebi.ac.uk/pdbsum/8uhe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uhe ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/B4WIH2_SYNS7 B4WIH2_SYNS7] 
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Far-red light photoacclimation, or FaRLiP, is a facultative response exhibited by some cyanobacteria that allows them to absorb and utilize lower energy light (700 to 800 nm) than the wavelengths typically used for oxygenic photosynthesis (400 to 700 nm). During this process, three essential components of the photosynthetic apparatus are altered: photosystem I, photosystem II, and the phycobilisome. In all three cases, at least some of the chromophores found in these pigment-protein complexes are replaced by chromophores that have red-shifted absorbance relative to the analogous complexes produced in visible light. Recent structural and spectroscopic studies have elucidated important features of the two photosystems when altered to absorb and utilize far-red light, but much less is understood about the modified phycobiliproteins made during FaRLiP. We used single-particle, cryo-electron microscopy to determine the molecular structure of a phycobiliprotein core complex comprising allophycocyanin variants that absorb far-red light during FaRLiP in the marine cyanobacterium Synechococcus sp. PCC 7335. The structure reveals the arrangement of the numerous red-shifted allophycocyanin variants and the probable locations of the chromophores that serve as the terminal emitters in this complex. It also suggests how energy is transferred to the photosystem II complexes produced during FaRLiP. The structure additionally allows comparisons with other previously studied allophycocyanins to gain insights into how phycocyanobilin chromophores can be tuned to absorb far-red light. These studies provide new insights into how far-red light is harvested and utilized during FaRLiP, a widespread cyanobacterial photoacclimation mechanism.

Structure of the antenna complex expressed during far-red light photoacclimation in Synechococcus sp. PCC 7335.,Gisriel CJ, Shen G, Brudvig GW, Bryant DA J Biol Chem. 2023 Dec 21:105590. doi: 10.1016/j.jbc.2023.105590. PMID:38141759<ref>PMID:38141759</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 8uhe" style="background-color:#fffaf0;"></div>
== References ==
<references/>
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</StructureSection>
[[Category: Large Structures]]
[[Category: Synechococcus sp. PCC 7335]]
[[Category: Brudvig GW]]
[[Category: Bryant DA]]
[[Category: Gisriel CJ]]
[[Category: Shen G]]