View source for 8uy0


==Consensus olfactory receptor consOR2 bound to S-carvone and in complex with mini-Gs trimeric protein==
<StructureSection load='8uy0' size='340' side='right'caption='[[8uy0]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8uy0]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UY0 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0WU:(5S)-2-METHYL-5-(PROP-1-EN-2-YL)CYCLOHEX-2-EN-1-ONE'>0WU</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uy0 OCA], [https://pdbe.org/8uy0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uy0 RCSB], [https://www.ebi.ac.uk/pdbsum/8uy0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uy0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GBG2_HUMAN GBG2_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Lama glama]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Billesboelle CB]]
[[Category: Del Torrent CL]]
[[Category: Manglik A]]