View source for 8vcw


==X-Ray Crystal Structure of the biotin synthase from B. obeum==
<StructureSection load='8vcw' size='340' side='right'caption='[[8vcw]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8vcw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Blautia_obeum Blautia obeum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8VCW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8VCW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DTB:6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC+ACID'>DTB</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8vcw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8vcw OCA], [https://pdbe.org/8vcw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8vcw RCSB], [https://www.ebi.ac.uk/pdbsum/8vcw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8vcw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A5ZUL4_9FIRM A5ZUL4_9FIRM] Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.[HAMAP-Rule:MF_01694]
__TOC__
</StructureSection>
[[Category: Blautia obeum]]
[[Category: Large Structures]]
[[Category: Grove TL]]
[[Category: Lachowicz JC]]