View source for 8vyq


==Cryo-EM Structure of the BRAF V600K monomer==
<StructureSection load='8vyq' size='340' side='right'caption='[[8vyq]], [[Resolution|resolution]] 4.43&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8vyq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8VYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8VYQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.43&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8vyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8vyq OCA], [https://pdbe.org/8vyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8vyq RCSB], [https://www.ebi.ac.uk/pdbsum/8vyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8vyq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/1433Z_HUMAN 1433Z_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.<ref>PMID:9360956</ref> <ref>PMID:14578935</ref> <ref>PMID:15071501</ref> <ref>PMID:15644438</ref> <ref>PMID:16376338</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Decossas M]]
[[Category: Jin T]]
[[Category: Lajoie D]]
[[Category: Lavoie H]]
[[Category: Maisonneuve P]]
[[Category: Therrien M]]