View source for 8wst


==Cryo-EM structure of Melanin-Concentrating Hormone Receptor 2 with MCH==
<StructureSection load='8wst' size='340' side='right'caption='[[8wst]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8wst]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8WST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8WST FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8wst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8wst OCA], [https://pdbe.org/8wst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8wst RCSB], [https://www.ebi.ac.uk/pdbsum/8wst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8wst ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Gu Y]]
[[Category: He Q]]
[[Category: Hu W]]
[[Category: Shan H]]
[[Category: Wu C]]
[[Category: Wu K]]
[[Category: Xu HE]]
[[Category: Yuan Q]]
[[Category: Zhang Y]]
[[Category: Zhao L]]