View source for 8xig


==The crystal structure of the AEP domain of MPXV E5==
<StructureSection load='8xig' size='340' side='right'caption='[[8xig]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8xig]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Monkeypox_virus Monkeypox virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XIG FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PPV:PYROPHOSPHATE'>PPV</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xig OCA], [https://pdbe.org/8xig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xig RCSB], [https://www.ebi.ac.uk/pdbsum/8xig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xig ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PG117_MONPV PG117_MONPV] Multifunctional protein required for genome uncoating and replication. Major viral uncoating protein that is required for the release of the viral genome from incoming viral cores containing the viral DNA genome. Possesses an ATPase activity that is required for hexamerization and uncoating.[UniProtKB:P04305]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Monkeypox virus]]
[[Category: Gan J]]
[[Category: Zhang W]]