View source for 8xik


==Structure of acyltransferase GWT1 in complex with manogepix(APX001A)==
<StructureSection load='8xik' size='340' side='right'caption='[[8xik]], [[Resolution|resolution]] 3.55&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8xik]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XIK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XIK FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.55&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1LVI:3-[3-[[4-(pyridin-2-yloxymethyl)phenyl]methyl]-1,2-oxazol-5-yl]pyridin-2-amine'>A1LVI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xik OCA], [https://pdbe.org/8xik PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xik RCSB], [https://www.ebi.ac.uk/pdbsum/8xik PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xik ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GWT1_YEAST GWT1_YEAST] Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins.<ref>PMID:12714589</ref> <ref>PMID:12753194</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Dai XL]]
[[Category: Deng D]]
[[Category: Li JL]]
[[Category: Liu XZ]]
[[Category: Wang X]]