View source for 8xkw


==Structure of the TOM40 complex unannealed==
<StructureSection load='8xkw' size='340' side='right'caption='[[8xkw]], [[Resolution|resolution]] 3.64&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8xkw]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XKW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XKW FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.64&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xkw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xkw OCA], [https://pdbe.org/8xkw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xkw RCSB], [https://www.ebi.ac.uk/pdbsum/8xkw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xkw ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TOM22_YEAST TOM22_YEAST] Central component of the TOM (translocase of outer membrane) receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM20 and TOM70 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore. Docks TOM20 and TOM70 for interaction with the general TOM40 import pore (GIP) complex. May regulate the TOM machinery organization, stability and channel gating.<ref>PMID:10519552</ref> <ref>PMID:11276259</ref> <ref>PMID:7760834</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Shen QT]]
[[Category: Yang LY]]