View source for 8xwf


==Structure of CXCR2 bound to CXCL3 (Ligand-receptor focused map)==
<StructureSection load='8xwf' size='340' side='right'caption='[[8xwf]], [[Resolution|resolution]] 3.65&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8xwf]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XWF FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.65&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xwf OCA], [https://pdbe.org/8xwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xwf RCSB], [https://www.ebi.ac.uk/pdbsum/8xwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xwf ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CXCL3_HUMAN CXCL3_HUMAN] Ligand for CXCR2 (By similarity). Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes.<ref>PMID:10095777</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Banerjee R]]
[[Category: Ganguly M]]
[[Category: Nureki O]]
[[Category: Saha S]]
[[Category: Sano FK]]
[[Category: Sharma S]]
[[Category: Shihoya W]]
[[Category: Shukla AK]]