View source for 8xwx


==Crystal structure of FIS1-BAP31 complex from human==
<StructureSection load='8xwx' size='340' side='right'caption='[[8xwx]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8xwx]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8XWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8XWX FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.69&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8xwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8xwx OCA], [https://pdbe.org/8xwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8xwx RCSB], [https://www.ebi.ac.uk/pdbsum/8xwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8xwx ProSAT]</span></td></tr>
</table>
== Disease ==
[https://www.uniprot.org/uniprot/BAP31_HUMAN BAP31_HUMAN] BCAP31 is deleted in the chromosome Xq28 deletion syndrome which involves BCAP31 and the and the promoter region of ABCD1.
== Function ==
[https://www.uniprot.org/uniprot/BAP31_HUMAN BAP31_HUMAN] May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis.<ref>PMID:9396746</ref> <ref>PMID:10958671</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Bong SM]]
[[Category: Lee BI]]
[[Category: Nguyen MD]]